What is Mohs Surgery?

Originally developed in the 1930s, Mohs micrographic surgery has been refined into the most advanced, precise, and effective treatment for an increasing variety of skin cancer types. With the Mohs technique, physicians can precisely identify and remove an entire tumor while leaving the surrounding healthy tissue intact and unharmed. It is accepted as the single most effective technique for removing Basal Cell Carcinoma and Squamous Cell Carcinoma (BCCs and SCCs), the two most common skin cancers.

The Mohs procedure involves surgically removing skin cancer layer by layer and examining the tissue under a microscope until healthy, cancer-free tissue around the tumor is reached. Mohs surgery has the highest success rate of all treatments for skin cancer – up to 99%.

Advantages of Mohs Surgery

Mohs surgery is unique and so effective because of the way the removed tissue is microscopically examined, evaluating 100% of the surgical margins. The pathology is reviewed on site by the Mohs surgeon, who is specially trained in the reading of these slides, who can then remove more tissue if the margins are not clear. Advantages of Mohs surgery include:

• Ensuring complete cancer removal during surgery, virtually eliminating the chance of the cancer growing back.
• Minimizing the amount of healthy tissue lost.
• Maximizing the functional and cosmetic outcome resulting from surgery.
• Repairing the site of the cancer the same day the cancer is removed, in most cases.
• Curing skin cancer when other methods have failed.
• Other skin cancer treatment methods blindly estimate the amount of tissue to treat, which can result in the
unnecessary removal of healthy skin tissue and tumor re-growth if any cancer is missed.

Which Cancers Need Mohs Surgery?

Mohs surgery offers the highest cure rate among treatments for skin cancer and can be used for practically any type of skin cancer. There are many other acceptable skin cancer treatment options including freezing (cryosurgery), scraping & burning, surgical removal. (excision), and laser surgery, which all require the surgeon to estimate how extensively to treat the area around the tumor. There are many advantages to Mohs surgery compared to other other skin cancer treatments including its high cure rate and cost-effectiveness. It is especially appropriate for skin cancers that:

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    Develop on areas where preserving cosmetic appearance and function are important

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    Have recurred after previous treatment or are likely to recur

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    Are located in scar tissue

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    Are large

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    Have edges that are ill-defined

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    Grow rapidly

The Mohs Procedure

The Mohs surgery procedure seems simple: the surgeon removes the cancer, carefully checks to be sure the he or she got it all, then repairs the wound. American College of Mohs Surgery members, however, train in and practice the complex nuances of this process for years so they are prepared to handle any situation they may encounter. The steps followed for the Mohs surgical procedure are:

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    A surgery starts with surgeon examining the visible lesion and planning what tissue to remove. The patient then receives local anesthesia.

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    The surgeon removes the visible portion of the tumor using careful surgical techniques.

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    The surgeon removes a layer of skin and divides it into sections. A map is drawn to track where each portion of tissue originated.

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    The surgeon uses a microscope to examine each section of tissue in search of remaining cancer.

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    If the surgeon finds cancer cells under the microscope, he or she marks their location on the “map” and removes another deeper layer of skin.

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    The process stops when there is no longer evidence of cancer. The surgeon discusses reconstruction options and post-operative care.

Mohs Surgery Post-Operative Care

Although Mohs micrographic surgery has an extremely high success rate that frequently prevents skin cancer from recurring at the same site, it is very important to monitor your skin since you are already prone to skin cancer. Your dermatologist may arrange a series of follow up appointments that may extend many years into the future.

After a Mohs surgery procedure, most patients find the recovery process simple and easy thanks to the streamlined surgical approach that leaves surrounding tissue unharmed. You may or may not undergo a repair process to mend the wound left by the surgery. A number of different reconstruction options exist, and instructions for aftercare are different depending on which approach the surgeon takes. The surgeon and his or her medical team will provide you with detailed instructions to follow at home. These instructions will include:

  • Information about when to change bandages and how to clean the surgical site
  • Medication information about prescription or over-the-counter pills or topical ointments
  • A timeline for when you can return to certain activities, such as wearing makeup or exercising
  • A schedule of follow-up appointments to remove any stitches and monitor your healing
  • Recommendations for treating your Mohs surgery scar to ensure it heals and fades quickly

Frequently Asked Questions

Why Is It Called Mohs Surgery? Is Mohs an Acronym?

The term “Mohs” refers to Dr. Frederic Mohs, Professor of Surgery at the University of Wisconsin, who developed this surgical technique in the 1930s. The technique has undergone many refinements and has come to be known as “Mohs micrographic surgery” or simply “Mohs surgery” in honor of Dr. Mohs.

What is Mohs Surgery?

Dr. Mohs recognized that a skin cancer often resembles the “tip of the iceberg” with more tumor cells growing downward and outward into the skin like the roots of a tree. These “roots” are not visible with the naked eye, but can be seen under a microscope.

Mohs surgery is a highly specialized and precise treatment for skin cancer in which the cancer is removed in stages, one tissue layer at a time. It is an outpatient procedure, performed under local anesthesia, and is distinguished by a specific technique of tissue examination that is unique to Mohs surgery. Although other surgical specialists may check excision margins, this form of pathologic examination of the tissue is not the same as Mohs surgery.

Once a tissue layer is removed, its edges are marked with colored dyes, and a map of the specimen is created. The tissue is then processed onto microscope slides by a Mohs histotechnician. These slides are carefully examined under the microscope by the Mohs surgeon so that any microscopic roots of the cancer can be precisely identified and mapped. If cancer cells are seen, an additional tissue layer is removed only in areas where the cancer is still present, leaving normal skin intact. This saves as much normal, healthy skin as
possible.

Once the cancer has been removed, the Mohs surgeon will explain options for repair of the wound, including natural healing (granulation), stitching the wound together using a side-to-side closure, or using a skin flap or graft.

It’s important to choose a fellowship trained Mohs surgeon who is a member of the American College of Mohs Surgery. Mohs College surgeons have undergone at least 1 year of fellowship training beyond dermatology residency, which allows for additional experience in all of these specialized processes and techniques.

I Don’t See Anything After My Biopsy. Do I Really Need to be Treated?

Yes. Following a biopsy, your skin cancer may no longer be visible. However, the surface lesion that was removed can represent the “tip of the iceberg.” More tumor cells may remain in the skin. These can continue to grow downward and outward, like roots of a tree. These “roots” are not visible with the naked eye. If they are not removed, the tumor will likely reappear and require more extensive surgery.

Tumors that are neglected can spread deeply into the skin and invade nearby structures. On rare occasions, these cancerous cells can metastasize to lymph nodes and other organs in the body.

Why Does My Skin Cancer Need To Have Mohs Surgery?

Mohs surgery has the highest cure rate. It is appropriate for most skin cancers and especially suitable for skin cancer that:

• Is in an area where it is important to preserve healthy tissue for maximum functional and cosmetic result.
• Was treated previously and has come back.
• Is located near scar tissue.
• Is large.
• Does not have clearly defined edges.
• Is growing rapidly or uncontrollably.
• Is of an aggressive subtype (i.e., sclerosing or infiltrating basal cell carcinoma).
• Develops in organ transplant or lymphoma patients.

Please note: the above list is not exhaustive of all of the instances where Mohs surgery is the most appropriate option for your skin cancer.

How Long Does Mohs Surgery Take?

Although Mohs surgery can take longer than other techniques to perform, advances in technology, such as automated staining of tissue samples, have made it quicker. While it is impossible to predict exactly what timeframe to expect for each Mohs surgery procedure, the entire procedure usually lasts several hours. Rarely, clearing the tumor and reconstructing the defect can take the better part of a day. A consultation with the Mohs surgeon prior to your procedure will allow for the surgeon to understand the unique qualities of your situation and enable him/her to more clearly estimate the extent of the timeframe for the surgery.

Will Mohs Surgery Leave a Scar?

Yes. As will any treatment for skin cancer, Mohs surgery will leave a scar.

Mohs surgery preserves as much healthy skin as possible and maximizes options for repairing the surgical defect, once the tumor is completely removed. Once the Mohs surgeon has completely removed your skin cancer through Mohs surgery, reconstruction for optimizing the final functional and cosmetic result becomes the highest priority. Generally, a post-surgical scar improves with time and can take up to 1 year or more to fully mature. As your surgical site heals, new blood vessels can appear and support the healing changes occurring underneath the skin. This can result in the reddish appearance of the scar. This change is temporary and will
improve with time.

In addition, the normal healing process involves a period of skin contraction, which often peaks 4 to 6 weeks after the surgery. This may appear as a bumpiness or hardening of the scar. On the face, this change is nearly always temporary and the scar will soften and improve with time. If you have a history of abnormal scarring, such as hypertrophic scars or keloids, or if there are problems with the healing of your scar, injections or other treatments may be used to optimize the cosmetic result. Your Mohs surgeon is available for you
throughout the healing process to discuss any concerns that may arise.

Is Mohs Surgery The Most Cost-Effective Treatment Option?

When assessing the cost-effectiveness of Mohs surgery there are several factors to consider. Because of the number of personnel involved as well as the advanced technology required, the initial procedure is often more costly than other treatment methods. However, because of the procedure’s high success rate, most patients require only a single surgery. This surgery usually includes the repair of the
wound as well. While other methods might initially be less expensive than Mohs surgery, additional surgeries and pathology readings are required to repair the wound and to treat the cancer if it is not completely removed. Each of these additional surgeries and pathology readings will require separate fees, while a single Mohs surgery procedure includes all of these into one fee.

What is Skin Cancer?

Skin cancer is the most common of all cancers. It affects more than two million Americans each year, and the numbers are on the rise. Skin cancer is the easiest cancer to cure, as long as it is diagnosed and treated early. If skin cancer is not treated early it can lead to disfigurement and even death.

Each year there are more new cases of skin cancer than the combined incidence of cancers of the breast, prostate, lung and colon.

One in five Americans will develop skin cancer in the course of a lifetime.

Types of Skin Cancer

  • Actinic Keratoses (AKs)

    Scaly, crusty growths caused by damage from the sun’s UV rays. They are often elevated or rough in texture.

     

  • Basal Cell Carcinoma

    Most common type of skin cancer, appears on skin exposed to the sun, such as the face, scalp, neck, hands, and arms.

  • Malignant Melanoma

    Develops from the pigment-producing cells (melanocytes) in the skin and can grow quickly and spread to other parts of the body.

  • Squamous Cell Carcinoma

    A common type of skin cancer that typically appears on sun-exposed skin because of increased UV ray exposure.

     

CAUSES

Skin cancer is the uncontrolled growth of abnormal skin cells. It occurs when unrepaired DNA damage to skin cells triggers mutations, or genetic defects, that lead the skin cells to multiply rapidly and form malignant tumors. This DNA damage is most often caused by ultraviolet radiation from sunshine or tanning beds.

RISK FACTORS

Anyone can get skin cancer, even those who have skin of color. Most people who get skin cancer, however, have lighter skin. People who are more likely to get skin cancer:

  • Excessive time spent in the sun
  • Use tanning beds or sun lamps
  • Resided in an area that gets intense sunlight, such as Florida, the Caribbean, or northern Australia.

Any length of exposure, even if it occurred years ago or was short, increases your risk.

There are also some general characteristics which may increase a person’s risk for getting skin cancer, which include:

  • A person’s skin type and the moles on one’s skin
  • Family history of skin cancer
  • Medical history
  • Exposure to chemicals
  • Tobacco

SYMPTOMS

The most common warning sign of skin cancer is a change to your skin. And the most common change is something growing on your skin. This growth can appear on the skin in many ways.

DIAGNOSIS

To diagnose skin cancer, a dermatologist looks at the skin. A dermatologist will carefully examine growths, moles, and dry patches.

To get a better look, a dermatologist may use a device called a dermatoscope. The device shines light on the skin. It magnifies the skin. This helps the dermatologist to see pigment and structures in the skin.

If a dermatologist finds something that looks like skin cancer, the dermatologist will take a sample of all or part of the suspicious skin. and the sampled skin will be sent to a lab where it can be examined under a microscope. A biopsy should not cause anxiety. The discomfort and risks are minimal.

Treatment

A dermatologist selects the appropriate treatment by considering the type of skin cancer, its location on the body, whether it is aggressive, the stage of the cancer, and the patient’s overall health.

  • Surgical treatment (Excision, Mohs surgery, curretage and electrodesiccation)
  • Immunotherapy
  • Cryosurgery
  • Chemotherapy applied to the skin
  • Chemotherapy
  • Photodynamic therapy
  • Radiation therapy

 

To protect your skin from the sun, seek shade between 10 AM and 4 PM, avoid burning and UV tanning beds, and wear protective clothing. Use a broad-spectrum (UVA/UVB) sunscreen with at least SPF 15 daily. Apply sunscreen to your body 30 minutes before going outside and reapply every two hours or after swimming. Keep babies out of the sun, examine your skin monthly, and see a physician yearly for a professional skin exam.

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FAQs

What does SPF mean?

SPF means “Sun Protection Factor.” It is a measure of how well the sunscreen protects you from harmful UV rays from the sun. Sunscreen must be re-applied every two to three hours, even if it has a high SPF number. Adults and children should always wear at least SPF 15.

What SPF is needed to prevent skin cancer?

To lower the chance of skin cancer, adults and children should always wear at least SPF 15.

Do tanning beds cause skin cancer?

Recent research says that yes, tanning beds can cause cancer. The World Health Organization strongly urges all people to avoid using tanning beds, especially those under the age of 18.

Are there different types of skin cancer?

There are different types of skin cancer. Each type is named after which type of cell it begins in. The three most common types of skin cancer are melanoma, basal cell carcinoma, and squamous cell carcinoma.

How can I tell if I have skin cancer?

Only a doctor can tell if you have skin cancer. Be sure to talk to your doctor if you notice any unusual moles, bumps, or red patches, or if you notice a change in any moles you already have. It may be a good idea to perform a monthly self skin check. Talk to your doctor if you notice any new moles, bumps or rough patches that are unusual, or if you notice a change in any you already had. Things to look for include: changes in any moles, bumps, or rough patches, moles with a dark color (blue, black, purple, green, etc), moles that are not the same color or shade throughout, moles with irregular/wavy borders, moles that are asymmetrical (one side looks different than the other side), moles that are bigger around than the eraser on the top of a pencil, or spots that itch or bleed.

Do I have a higher chance of getting skin cancer if a family member had it?

If a family member had skin cancer, you may have a higher chance of getting it. Some things, such as skin type, environment, and lifestyle are similar among family members.

If I have BCC, am I at greater risk of developing other skin cancers?

Yes. Studies show that people who have one skin cancer are at greater risk of developing another skin cancer. Perform regular skin self- examinations, and protect your skin every day. Be sure to keep all appointments with your dermatologist, and make an immediate appointment if you notice anything changing, itching, or bleeding on your skin.

Can anyone get BCC?

Yes. People of all skin colors can get BCC, although it is much more common in light skinned people.

How can I prevent AKS?

Daily sun protection is an important part of skin cancer prevention. The following are some of The Skin Cancer Foundation’s list of prevention tips:

• Seek the shade, especially between 10 AM and 4 PM.
• Do not let your skin burn.
• Avoid tanning and never use UV tanning beds.
• Cover up with clothing, including a broad-brimmed hat and UV-blocking sunglasses.
• Use a broad spectrum (UVA/UVB) sunscreen with an SPF of 15 or higher (most dermatologist recommend 30 or higher with zinc) every day. For extended outdoor activity, use a water-resistant, broad spectrum (UVA/UVB) sunscreen with an SPF of 30 or higher (again, most dermatologist recommend a higher SPF, of 50 or higher if planning on being outside).
• Apply 1 ounce (2 tablespoons, or 1 shot glass) of sunscreen to your entire body 30 minutes before going outside. Reapply every two hours or immediately after swimming or excessive sweating.

If I have SCC, am I at greater risk of developing other skin cancers?

Yes. Studies show that people who have one skin cancer are at greater risk of developing another skin cancer. Perform regular skin self- examinations, and protect your skin every day. Be sure to keep all appointments with your dermatologist, and make an immediate appointment if you notice anything changing. itching, or bleeding on your skin.

What is melanoma?

Melanoma is the most deadly type of skin cancer. It can take many shapes and appearances. Melanoma is usually a dark color like brown, blue, or black. Other signs to look for include: irregular borders, asymmetry (one half looks different than the other half), and size – melanomas are usually large (bigger than a pencil eraser)

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